|LETTER TO EDITOR
|Year : 1996 | Volume
| Issue : 2 | Page : 134-135
S K Malhotra
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Malhotra S K. Sneddon-wilkinson disease. Indian J Dermatol Venereol Leprol 1996;62:134-5
| To the Editor,|| |
Please refer to the article ' Sneddon-Wilkinson disease More Details and arthritis' by S K Bose published in the Journal (1995; 61:231-2). I would like to share few of my observations on this disease.
Sneddon-Wilkinson disease (SWD) is no doubt rare, yet quite a number of cases are seen in the dermatology clinic of a referral hospital like ours. Recently we had a female patient aged 40 years presenting with the classical bilateral symmetrical lesions of SWD on flanks, trunk and limbs. The lesion were present on the periphery of a diffuse erythema. The older lesions were replaced by sheets of desquamation. Patient was a known case of bronchial asthma for the last 20 years. Biochemical investigations were within normal limits. Repeated cultures from the pustules were sterile. Histopathology revealed a subcorneal bulla containing neutrophils and a few eosinophils. No definite acantholytic cells were seen. Basal layer was intact. Dermis showed few dilated blood vessels which were surrounded by neutrophils, eosinophils and few mononuclear cells.
Two important findings recorded in this case were:
- (1) Crops of lesions were preceded by severe burning, pain and tenderness of the affected areas of the skin.
- (2) Lesions were found over palms and soles.
Mild to moderate itching is present in most of the cases but features like burning and pain are poorly documented in the literature, palms and soles are rarely involved in this disease as was seen in our case.,
| References|| |
|1.||Mittal RR, Singla A, Gill SS.Subcorneal pustular dermatosis during summer months. Ind J Dermatol Venereol Leprol 1993;59:288-9. |
|2.||Haber H, Wells GC. Subcorneal pustular dermatosis of the soles. Br J Dermatol 1959;71:253-5. [PUBMED] |
|3.||Hellier FF. Generalized pustular bacterid: Its relationship to pustular dermatosis of Sneddon and Wilkinson. Br J Dermatol 1956;68:395-9. [PUBMED] |