Indexed with PubMed and Science Citation Index (E) 
Users online: 5481 
     Home | Feedback | Login 
About Current Issue Archive Ahead of print Search Instructions Online Submission Subscribe What's New Contact  
  Navigate here 
   Next article
   Previous article 
   Table of Contents
 Resource links
   Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
   [PDF Not available] *
   Citation Manager
   Access Statistics
   Reader Comments
   Email Alert *
   Add to My List *
* Registration required (free)  

  In this article
   To the Editor,

 Article Access Statistics
    PDF Downloaded0    
    Comments [Add]    

Recommend this journal


Year : 1996  |  Volume : 62  |  Issue : 2  |  Page : 134-135

Sneddon-wilkinson disease

Correspondence Address:
S K Malhotra

Login to access the Email id

Source of Support: None, Conflict of Interest: None

PMID: 20948014

Rights and PermissionsRights and Permissions

How to cite this article:
Malhotra S K. Sneddon-wilkinson disease. Indian J Dermatol Venereol Leprol 1996;62:134-5

How to cite this URL:
Malhotra S K. Sneddon-wilkinson disease. Indian J Dermatol Venereol Leprol [serial online] 1996 [cited 2020 Feb 26];62:134-5. Available from: http://www.ijdvl.com/text.asp?1996/62/2/134/4352

  To the Editor, Top

Please refer to the article ' Sneddon-Wilkinson disease More Details and arthritis' by S K Bose published in the Journal (1995; 61:231-2). I would like to share few of my observations on this disease.

Sneddon-Wilkinson disease (SWD) is no doubt rare, yet quite a number of cases are seen in the dermatology clinic of a referral hospital like ours. Recently we had a female patient aged 40 years presenting with the classical bilateral symmetrical lesions of SWD on flanks, trunk and limbs. The lesion were present on the periphery of a diffuse erythema. The older lesions were replaced by sheets of desquamation. Patient was a known case of bronchial asthma for the last 20 years. Biochemical investigations were within normal limits. Repeated cultures from the pustules were sterile. Histopathology revealed a subcorneal bulla containing neutrophils and a few eosinophils. No definite acantholytic cells were seen. Basal layer was intact. Dermis showed few dilated blood vessels which were surrounded by neutrophils, eosinophils and few mononuclear cells.

Two important findings recorded in this case were:

  1. (1) Crops of lesions were preceded by severe burning, pain and tenderness of the affected areas of the skin.

  2. (2) Lesions were found over palms and soles.

Mild to moderate itching is present in most of the cases but features like burning and pain are poorly documented in the literature,[1] palms and soles are rarely involved in this disease as was seen in our case.[2],[3]

  References Top

1.Mittal RR, Singla A, Gill SS.Subcorneal pustular dermatosis during summer months. Ind J Dermatol Venereol Leprol 1993;59:288-9.  Back to cited text no. 1    
2.Haber H, Wells GC. Subcorneal pustular dermatosis of the soles. Br J Dermatol 1959;71:253-5.  Back to cited text no. 2  [PUBMED]  
3.Hellier FF. Generalized pustular bacterid: Its relationship to pustular dermatosis of Sneddon and Wilkinson. Br J Dermatol 1956;68:395-9.  Back to cited text no. 3  [PUBMED]  


Print this article  Email this article
Previous article Next article


Online since 15th March '04
Published by Wolters Kluwer - Medknow