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LETTER TO EDITOR
Year : 1996  |  Volume : 62  |  Issue : 2  |  Page : 131

Why lesions of morphoea are often hyperpigmented ?




Correspondence Address:
Sandipan Dhar


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Source of Support: None, Conflict of Interest: None


PMID: 20948010

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How to cite this article:
Dhar S, Dhar S. Why lesions of morphoea are often hyperpigmented ?. Indian J Dermatol Venereol Leprol 1996;62:131

How to cite this URL:
Dhar S, Dhar S. Why lesions of morphoea are often hyperpigmented ?. Indian J Dermatol Venereol Leprol [serial online] 1996 [cited 2019 Dec 15];62:131. Available from: http://www.ijdvl.com/text.asp?1996/62/2/131/4349



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The lesions of morphoea are characterized by indurated areas of skin, which at first are faintly purplish or mauve in colour. After a few weeks or months, they lose their colour, especially in the central part and appear as thickened waxy ivory coloured areas with a characteristic lilac border.[1] In Indians with mostly type IV or type V skin colour, we rarely appreciate the purplish or mauve colour and lilac border in the lesions of morphoea. Instead, in most of our patients we observe mild hyperpigmentation over the morphoea plaques. In the standard text[1] these hyperpigmented patches are stated to be present at the very beginning of morphoea lesion(s) or at the site of resolving plaque(s). However, we see these patches mostly over the well developed plaques of morphoea. The pathomechanism of such hyperpigmentation has not been elucidated in the standard textbooks.[1],[2]

We have been interested to look into this aspect and to find out the status of melanocyte and basal cell layer in the histopathological sections of morphoea lesions. On Fontana-Masson stained sections, we have found that there is increased melanocytic activity in the form of prominent melanocytes in the basal cell layer. It appears that there is increased melanin synthesis inside the melanocytes. There is no basal cell degeneration and melanin incontinence. The first author has been observing this histopathological phenomenon for the last 6 years.

 
  References Top

1.Rowell NR, Goodfield MJD. The connective tissue diseases. In : Champion RH, Burton JL, Ebling FJG, eds. Textbook of dermatology. Oxford : Blackwell Scientific Publications, 1992:2163-2294.  Back to cited text no. 1    
2.Lever WF, Lever-Schaumburg G. Histopathology of the skin. Philadelphia : J B Lipincott Company, 1990.  Back to cited text no. 2    




 

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