IADVL
Indexed with PubMed and Science Citation Index (E) 
 
Users online: 2796 
     Home | Feedback | Login 
About Current Issue Archive Ahead of print Search Instructions Online Submission Subscribe What's New Contact  
  Navigate here 
  Search
 
   Next article
   Previous article 
   Table of Contents
  
 Resource links
   Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
  Related articles
   [PDF Not available] *
   Citation Manager
   Access Statistics
   Reader Comments
   Email Alert *
   Add to My List *
* Registration required (free)  

 
  In this article
   Abstract
   Introduction
   Case Report
   Discussion
   References

 Article Access Statistics
    Viewed6751    
    Printed109    
    Emailed2    
    PDF Downloaded0    
    Comments [Add]    

Recommend this journal

 


 
CASE REPORT
Year : 1996  |  Volume : 62  |  Issue : 2  |  Page : 110-111

Lichen planus and lupus erythematosus overlap syndrome




Correspondence Address:
Adarsh Chopra


Login to access the Email id

Source of Support: None, Conflict of Interest: None


PMID: 20947996

Rights and PermissionsRights and Permissions

  Abstract 

A 45-year-old woman with livid plaques showing central atrophy and erythematous vesicular borders over both dorsa of feet and buttocks, and follicular and papular lesions over buttocks and lumbar area, was difficult to diagnose as either lichen planus (LP) or lupus erythematosus (LE). The histological studies from two places showed features of both LE and LP. Laboratory findings were within normal limits first, but follow up studies for two years showed persistent albuminurea, leucopenia, arthritis and erythema over the exposed areas with same histology suggesting that eruption may be an unusual variant of LE.


Keywords: Lichen planus, Lupus erythematosus


How to cite this article:
Chopra A, Bahl R K, Puri R K, Gill S S. Lichen planus and lupus erythematosus overlap syndrome. Indian J Dermatol Venereol Leprol 1996;62:110-1

How to cite this URL:
Chopra A, Bahl R K, Puri R K, Gill S S. Lichen planus and lupus erythematosus overlap syndrome. Indian J Dermatol Venereol Leprol [serial online] 1996 [cited 2019 Jun 16];62:110-1. Available from: http://www.ijdvl.com/text.asp?1996/62/2/110/4334



  Introduction Top


Discoid LE and LP are considered as distinct entities with characteristic clinical, histological and immunological features.[1] But rarely there have been reports of overlapping features of both disorders. The overlap syndrome has been characterized by clinical and histological criteria.[2] It consists of livid bluish red patches or plaques affecting the acral areas of the extremities that show a hypocellular or hypercellular lichenoid pattern in papillary dermis. Pruritus and photosensitivity are usually absent. Long term follow up may show a progression to SLE in some cases but persistence of skin lesions in others. We are reporting a female patient with features of both the diseases.


  Case Report Top


A 45-year-old female presented with asymptomatic well-defined scaly plaques showing central atrophy and erythematous vesicular borders over both the dorsa of feet and buttocks and follicular papular lesions over buttocks and lumbar area for the last 1 years. No other area was involved. The-scales were fine and adherent but on removing no follicular plugging was visible. There was no history of joint pains, fever, photosensitivity, neuropsychiatric disturbances, cough, and dyspnoea. Nails showed changes in the form of longitudinal ridges, pitting and sub-ungual hyperkeratosis. Left big toe nail showed median canaliculus and atrophy of proximal part of the nail. Routine blood tests were within normal limits. She was put on topical steroid cream but there was no response. After 6 months she complained of joint pains and mild to moderate fever and on investigations, haemoglobin was 8.5 mg%, leucocyte count was 3500/ mm3 and rest of the investigations were normal. At the same time she developed erythema over the butterfly area of face. Biopsy from the edge of the lesion on the foot showed hyperkeratosis, parakeratosis, acanthosis and elongation of rete ridges. At places there was sharpening of rete ridges giving saw-toothed appearance. Dermoepidermal junction showed linear band like round cell infiltration. Deeper dermis showed perivascular infiltrate and at places there was massive round cell infiltration.


  Discussion Top


Our patient had all the characteristic clinical and histological fearures of both LE and LP. Coexistence of these two diseases has been described by Romero et al.[3] The nail changes seen in our patient were consistent with LP.[4] Development of arthritis, fever and erythema over the photosensitive areas during two years of follow up led us to think that these lesions were a variant of LE. Same were the findings of Jamison et al.[2] Such cases should be followed up to confirm whether these are the coexistent diseases or unusual variant of LE.

 
  References Top

1.Black MM. Lichen planus and lichenoid eruptions. In: Rook A, Wilkinson DS, Ebling FJD, Champion RH, Burton JL, eds. Textbook of dermablogy. 4th edn. Oxford: Blackwell Scientific Publications, 1986:1681.  Back to cited text no. 1    
2.Jamison TH, Cooper NM, Wallace V, Epsteen. Lichen planus and discoid lupus erythematosus. Arch Dermatol 1978;1039-41.  Back to cited text no. 2    
3.Romero RW, Nesbitt LT Jr, Reed RJ. Unusual variant of lupus erythematosus. Arch Dermatol 1977;13:741-8.  Back to cited text no. 3    
4.Samman PD. Nails in lichen planus. Br J Dermatol 1961;73:288-92.  Back to cited text no. 4  [PUBMED]  




 

Top
Print this article  Email this article
Previous article Next article

    

Online since 15th March '04
Published by Wolters Kluwer - Medknow