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Year : 1996  |  Volume : 62  |  Issue : 1  |  Page : 62-63

Hypervitaminosis - A

Correspondence Address:
J N Dave

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Source of Support: None, Conflict of Interest: None

PMID: 20947982

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How to cite this article:
Dave J N, Vora N S, Cardoso B, G. Hypervitaminosis - A. Indian J Dermatol Venereol Leprol 1996;62:62-3

How to cite this URL:
Dave J N, Vora N S, Cardoso B, G. Hypervitaminosis - A. Indian J Dermatol Venereol Leprol [serial online] 1996 [cited 2020 Jan 21];62:62-3. Available from: http://www.ijdvl.com/text.asp?1996/62/1/62/4321

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A 10-year-old boy was being treated for night blindness with injectable and oral vitamin A for more than 3 months. He presented to us with well circumscribed itchy, dry, scaly, follicular lesions over knees, elbows and knuckles present for 15 days. Scalp hair was sparse, thin and dry. He complained of headache. There was no history of chest pain, palpitation or lymphadenopathy. There was no neurological deficit. Fundoscopic examination did not reveal any abnormality. Routine blood and urine analysis were within normal limits. Skeletal X-rays showed mild periosteal reaction. On histopathological examination moderate hyperkeratosis and focal inflammatory cell infiltration were seen.

Hypervitaminosis A occurs in an acute form due to ingestion of a large single dose of vitamin A and in a chronic form due to prolonged ingestion of more than 50000 iu of vitamin A.[1] Though serum vitamin A levels could not be done in our patient due to lack of facilities, the remarkable clinical improvement on vitamin A and restriction of vitamin A rich diets without any other medications pointed towards the clinical diagnosis of hypervitaminosis A.

  References Top

1.Weismann K. Nutrition and the skin. In: Champion RH, Burton JL, Ebling FJG, editors. Textbook of dermatology. London: Blackwell, 1992:2360.  Back to cited text no. 1    


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