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Year : 1995  |  Volume : 61  |  Issue : 6  |  Page : 383

Sister Mary Joseph's nodule as presenting sign of ovarian carcinoma

Correspondence Address:
C Arun Inamadar

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Source of Support: None, Conflict of Interest: None

PMID: 20953036

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How to cite this article:
Inamadar C A, Mavarkar L. Sister Mary Joseph's nodule as presenting sign of ovarian carcinoma. Indian J Dermatol Venereol Leprol 1995;61:383

How to cite this URL:
Inamadar C A, Mavarkar L. Sister Mary Joseph's nodule as presenting sign of ovarian carcinoma. Indian J Dermatol Venereol Leprol [serial online] 1995 [cited 2019 Oct 19];61:383. Available from: http://www.ijdvl.com/text.asp?1995/61/6/383/4287

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Malignant tumours have the ability to grow at sites distant from the primary site of origin. The umbilicus is a characteristic site, especially from cancer of the stomach (Sister Mary Joseph's nodules).[1] A case of umbilical metastasis from ovarian carcinoma is reported here.

A female aged 40 years presented with lesions in the umbilicus since 4 months.Except history of menorrhagia, patient did not have any symptom of significance. On examination hard nodule with superficial erosion was found in umbilical area. Per abdominal examination revealed an irregular slightly mobile, hard mass arising from pelvis in the left iliac fossa. Pervaginal examination confirmed our findings of pelvic mass. Routine haematological examination showed anaemia. USG of the abdomen revealed findings suggestive of bilateral serocystoadenomatous ovarian carcinoma.

The so called Sister MaryJoseph's nodule is formed by localization of metastatic tumours to the umbilicus. Powell et al reviewed 85 cases of Sister Mary Joseph's nodule and found the most common primary sites to be stomach, large bowel, ovary and pancreas.[2]

Brustaman and Seltzer have reported seven cases of umbilical metastasis from gynaecologic malignancies.[3] Umbilical metastasis were the presenting symptoms in 18 out of 40 cases, and were a major diagnostic feature in 28 cases.[4]

  References Top

1.Samitz MH. Umbilical metastasis from carcinoma of the stomach. Arch Dermatol 1975;111:1478-9.  Back to cited text no. 1  [PUBMED]  
2.Powell FC, Cooper AJ, Mass MC,et al. Sister Mary Joseph's nodule: a clinical and histologic study. J Am Acad Dermatol 1984;10:610-5.  Back to cited text no. 2    
3.Brustman L, Seltzer. Sister Joseph's nodule: seven cases of umbilical metastasis from gynaecologic malignancies. Gynaecol Oncology 1984;19:155-62.  Back to cited text no. 3    
4.Steck WD, Helwig EB. Tumors of the umbilicus. Cancer 1965;18:907-15.  Back to cited text no. 4    


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