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Year : 1995  |  Volume : 61  |  Issue : 6  |  Page : 339--341

Oral leucoplakia

1 Department of Otolaryngology, Institute of Medical Sciences, Baranas Hindu University, Varanasi, India
2 Department of Pathology, Institute of Medical Sciences, Baranas Hindu University, Varanasi, India

Correspondence Address:
R K Jain
C-8, New Medical Enclave, Baranas Hindu University, Varanasi-221005
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Source of Support: None, Conflict of Interest: None

PMID: 20953015

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Oral leucoplakia was predominantly seen in elderly age group. Addiction to tobacco was observed in majority of patients (80.8%). Clinically commonest site of involvement was buccal mucosa (67.33%), followed by labial mucosa (13.86%). Majority of patients (57.35%) w.ere having homogenous type of leucoplakia, followed by verrucous variety (25%). 26-48% cases were also having oral submucous fibrosis. Histologically various combinations of hyperkeratosis, hyperorthokeratosis and acanthosis were observed in 77.93% of cases. Dysplastic lesions were reported in 17.65% cases. In 80% of dysplastic lesions, band like infiltrate of mononuclear cells in subepithelial zone was seen. Malignant transformation was noticed in 2.94% cases. Excellent therapeutic results were obtained by cryosurgery. In resistant cases good results were observed with high dosage of vitamin A.


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Online since 15th March '04
Published by Wolters Kluwer - Medknow