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Year : 1995  |  Volume : 61  |  Issue : 5  |  Page : 324-325


Correspondence Address:
A Ghosh

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Source of Support: None, Conflict of Interest: None

PMID: 20953008

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How to cite this article:
Ghosh A, Shah S V, Dave J N, Vora N S, Roy K, Cardoso. Scleredema. Indian J Dermatol Venereol Leprol 1995;61:324-5

How to cite this URL:
Ghosh A, Shah S V, Dave J N, Vora N S, Roy K, Cardoso. Scleredema. Indian J Dermatol Venereol Leprol [serial online] 1995 [cited 2020 Apr 7];61:324-5. Available from: http://www.ijdvl.com/text.asp?1995/61/5/324/4259

  To the Editor, Top

An 8-year-old boy presented with sudden onset of thickened, taut skin over the neck, shoulders rapidly spreading to involve the face, upper trunk, arms and upper abdomen preceded with mild prodrome. Increased pigmentation was seen over affected areas with puffiness of face and inability to open the mouth. The skin was bound down, non-tender with non-pitting oedema. No clear line of demarcation could be detected between affected and unaffected skin. Distal upper extremities and lower limbs were remarkably free. The patient had pyoderma one month ago. There was no history of fever, joint pain or Raynaud's phenomenon in the past or present. Other systems were not involved. Routine haematological examination and urinalysis were within normal limits except ESR which was raised. ASO titre was high (250 Todd units/ml). Tests for Rheumatoid factor and LE cell phenomenon were negative. ECG and chest X-ray did not reveal any abnormality. Histopathology of biopsy specimen from scapular region stained with H and E showed characteristic findings[1] of scleredema. No specific treatment was given but the child showed spontaneous improvement from 3 weeks onwards and after 6 months there were no residual sign of disease. The characteristic clinical course, histopathological findings were somewhat similar to other documented cases of scleredema. [1,2] In view of the sudden onset, preceding history of pyoderma and raised ASO titre a streptococcal hypersensitivity reaction is suggested.

  References Top

1.Greenberg LM, Geppert C, Worthem HG, et al. Scleredema adultorum in children, Pediatrics 1963;32:1044-54.  Back to cited text no. 1    
2.Mulay DN, Mehta JS, Ahuja BB. Seleredema, Brief Review of literature and case reports. Ind J Dermatol Venereol Leprol 1968;34:57-63.  Back to cited text no. 2    


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