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LETTER TO EDITOR
Year : 1995  |  Volume : 61  |  Issue : 4  |  Page : 243-244

Naevus lipomatoides cutaneous superficialis



Correspondence Address:
PVS Prasad


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Source of Support: None, Conflict of Interest: None


PMID: 20952977

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How to cite this article:
Prasad P. Naevus lipomatoides cutaneous superficialis. Indian J Dermatol Venereol Leprol 1995;61:243-4

How to cite this URL:
Prasad P. Naevus lipomatoides cutaneous superficialis. Indian J Dermatol Venereol Leprol [serial online] 1995 [cited 2019 Aug 21];61:243-4. Available from: http://www.ijdvl.com/text.asp?1995/61/4/243/4230



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Naevus lipomatoides cutaneous superficialis (NLCS) was first described by Hoffmann and Zurhelle in 1921.[1] This is an uncommon naevus showing groups of soft populonodules of pale yellow colour. They start in the first two decades.[2] Only 8 cases of NLCS have been reported in Indian literatute[3] and around 130 cases in the world literature.[4] This condition is due to the presence of ectopic fat cells in the dermis which are derived from the perivascular mesenchymal tissue.[2]

A 35-year-old female was seen with multiple grouped asymptomatic nodules over the left hip. Lesions started at puberty and gradually increased in size. There was no family history of similar lesions. On examination there were multiple yellowish coloured grouped soft non-tender nodules varying in size from 0.5-2 cm, seen on the left hip. There was no systemic involvement.

A provisional differential diagnosis of xanthoma or soft papilloma was made. Biopsy was taken from one of the nodules. Histopathological examination revealed island of fat cells embedded in the collagen bundles of the dermis, surrounding the dermal blood vessels and almost extending upto the epidermis [Figure - 1].

NLCS is a developmental anomaly. Though no sex predilection was mentioned earlier in the literature most of the cases including our patient were females.[3],[4] There are two clinical forms, the one with zonal distribution occurs on the buttocks and presents from birth or childhood and the other domed or sessile papule beginning later in life and also occurring on the limbs.[5] The histopathology of this condition is characteristic. There is predominantly dermal collections of adipose tissue. Similar findings may also be seen with intradermal melanocytic naevi and Goltz syndrome both of which may be easily distinguished clinically from NLCS.[2] The lipocytes seen in the dermis are found to be immature and are postulated to arise from the pericytes as these are closely associated with dermal capillaries.[2] Comedo like plugs, cafe au lait spots, hypopigmented macules and ulceration over the lesions have all been described in a few cases, these were not observed in our patient.[5]

 
  References Top

1.Hoffmann E, Zurhelle E. Uber einen naevus lipomatodes cutaneus superficialis derlinken glutaalgegend. Arch Dermatol Syphilol 1921;130:327-33.  Back to cited text no. 1    
2.Lever WF, Lever GF. Tumours of fatty, muscular and osseous tissue. In: Histopathology of skin. 6th edn. Philadelphia: J B Lippincott company, 1983;652.  Back to cited text no. 2    
3.Thappa DM, Sharma RC, Lal S, et al. Naevus lipomatosus cutaneus superficialis-report of 2 cases. Ind J Dermatol Venereol Leprol 1992;58:27-9.  Back to cited text no. 3    
4.Chanoki M, Sugamoto l, Suzukie, et al. Naevus lipomatosus cutaneus superficialis of scalp. Cutis 1989;43:143-4.  Back to cited text no. 4    
5.Atherton DJ. Naevi and other developmental defects. In: Textbook of Dermatology (Champion RH, Burton JL, Ebling FLG, eds). 4th edn. Oxford: Blackwell Scientific Publications, 1992;467-8.  Back to cited text no. 5    


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