|Year : 1995 | Volume
| Issue : 3 | Page : 176-177
Congenital anomaly of the toes, microophthalmos and haemangioma
AK Mukhopadhyay, JN Dave, NS Vora, SV Shah, Ghosh
A K Mukhopadhyay
Source of Support: None, Conflict of Interest: None
A two-and-half month-old female infant with cavernous haemangioma, agenesis and syndactyly of toes, microophthalmia and microcornea is reported.
Keywords: Haemangioma, Toe abnormalities, Microophthalmia, Microcornea
|How to cite this article:|
Mukhopadhyay A K, Dave J N, Vora N S, Shah S V, Ghosh. Congenital anomaly of the toes, microophthalmos and haemangioma. Indian J Dermatol Venereol Leprol 1995;61:176-7
|How to cite this URL:|
Mukhopadhyay A K, Dave J N, Vora N S, Shah S V, Ghosh. Congenital anomaly of the toes, microophthalmos and haemangioma. Indian J Dermatol Venereol Leprol [serial online] 1995 [cited 2020 Feb 20];61:176-7. Available from: http://www.ijdvl.com/text.asp?1995/61/3/176/4195
| Introduction|| |
Cavernous haemangioma has been associated with many syndromes affecting one or more organs or systems.The present case describes a child with multiple abnormalities of the toes of both feet with cavernous haemangioma of the left supraauricular region along with left sided microophthalmos and microcornea.
| Case Report|| |
A two-and-half month-old female child born of a non-consanguineous marriage, presented with a cavernous haemangioma of the left supra-auricular region, which was present since birth. She also had agenesis of the first, second and third toes and syndactyly of the fourth and fifth toes of the right foot. The great toe of the left foot was hypoplastic and there was syndactyly of the remaining toes [Figure.:1]. The upper limbs were normal. The baby also had left sided microophthalmos and microcornea. She had no apparent abnormalities of any other system.
Roentgenological examination of the right foot revealed three tarsal bones and one each of the metatarsal and the phalanx, along with soft tissue atrophy. An X-ray of the left foot showed the absence of phalanges in the great toe, and soft tissue atrophy. A skeletal survey of the rest of the body was normal. Ultrasonography of the spine and abdomen revealed no abnormality. Ultrasonography of the brain, done through the fontanellae showed no evidence of hydrocephalous, haemangioma or brain atrophy.
On detailed enquiry, her mother gave no history of any major illness or exposure to radiation or drug except for iron and folic acid tablets during pregnancy. The mother had a spontaneous vaginal delivery. Other members of the family including her siblings were normal.
| Discussion|| |
Multiple genetic abnormalities involving the skeletal system and skin lesion have been described earlier.,, But this particular combination of agenesis, polysyndactyly and hypoplasia of different toes along with haemangioma and ocular abnormalities is unique and to the best of our knowledge has not been reported in the literature.
| References|| |
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|2.||Sharma RP, Gill RS, Dhir GG. Cutaneous haemangioma associated with nasal deformity. Ind J Dermatol Venereol Leprol 1983;49:175. |
|3.||Atherton DK. Naevi and other development defect. In: Textbook of dermatology (Champion RH, Burton JL, Ebling FJG, eds). 5th edn. Oxford: Blackwell Scientific publication, 1992;491-503. |
|4.||Sawhney MPS. Adult onset segmental cavernous haemangioma, varicose veins and limb atrophy-Klippel-Trenauney-Weber syndrome variant. Ind J Dermatol Venereol Leprol 1990;56:324. |
[Figure - 1]