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LETTER TO EDITOR
Year : 1995  |  Volume : 61  |  Issue : 1  |  Page : 63-64

Familial koilonychia with superimposed myxoid cyst




Correspondence Address:
R R Mittal


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Source of Support: None, Conflict of Interest: None


PMID: 20952886

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How to cite this article:
Mittal R R, Dhaliwal M S. Familial koilonychia with superimposed myxoid cyst. Indian J Dermatol Venereol Leprol 1995;61:63-4

How to cite this URL:
Mittal R R, Dhaliwal M S. Familial koilonychia with superimposed myxoid cyst. Indian J Dermatol Venereol Leprol [serial online] 1995 [cited 2019 Nov 12];61:63-4. Available from: http://www.ijdvl.com/text.asp?1995/61/1/63/4140



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16 patients of koilonychia in five generations of a family were reported in 1950 and later 12 patients, in four generations of another family were observed. [1,2] Familial koilonychia is not associated with congenital ectodermal, systemic or orthopaedic defects. Autosomal dominant inheritance with a high degree of penetrance has been reported.[1],[2] Pathogenesis of koilonychia has been discussed with two assumptions; one was that structural stress may be incorporated in the keratinization process of nail formation and second was that factors in nail matrix and proximal nail bed determine direction of nail growth, so if angulation of distal nail matrix is lower than proximal it will result in koilonychia.

One 40 years female had asymptomatic platynychia and koilonychia of all nails since early childhood. Lanulae of all nails were prominent in her. She also had a slightly painful, tender, progressive, pinkish, semitranslucent, 6 to 7 mm diameter, globular, cystic swelling with smooth shiny surface and central punctum, on the proximal half of left middle finger nail for past 1 year. A drop of thick fluid escaped from cyst few days back and distal to the cyst nail plate had some pits. Her 12 years son also had platynychia and koilonychia of all nails since early childhood [Figure - 1]. She was not aware of similar nail changes in her other relatives. General physical and systemic examinations were normal in both of them. No other genetic abnormality was seen. As far as we know this is the first case report of familial koilonychia from India.

The globular cystic swelling of left middle finger nail was diagnosed as myxoid cyst. Most probably it developed under thin and weak nail plate of koilonychia because of trauma associated with household work[3].





 
  References Top

1.Hellier FF. Hereditary Koilonychia. Br J Derm 1950; 62:213-4.  Back to cited text no. 1    
2.Bergeron JR, Stone OJ. Koilonychia : A Report of Familial Spoon Nails. Arch Dermatol April 1967; 95.  Back to cited text no. 2    
3.Stone OJ, Maberry JD. Spoon nails and clubbing : Review and Possible Structural Mechanisms. Text J Med 1965;61:620-7.  Back to cited text no. 3    


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Online since 15th March '04
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