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Year : 1995  |  Volume : 61  |  Issue : 1  |  Page : 56--57

Colchicine in the treatment of subcorneal pustular dermatosis

Department of Dermato-Venereologly, Medical College Hospital, Kottayam, India

Correspondence Address:
K Pavithran
Department of Dermato-Venereologly, Medical College Hospital, Kottayam
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Source of Support: None, Conflict of Interest: None

PMID: 20952880

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A male patient with subcorneal pustular dermatosis was initially treated with dapsone with excellent response. Since he developed hypersensitivity to dapsone, corticosteroid was given instead of dapsone. But steroid also was withdrawn since he developed hypertension and diabetes. There was relapse of skin lesions which were treated with oral colchicine, which has profound inhibitory effects on neutrophils. There was excellent therapeutic response to colchicine and the drug well-tolerated.

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Online since 15th March '04
Published by Wolters Kluwer - Medknow