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LETTER TO EDITOR
Year : 1994  |  Volume : 60  |  Issue : 3  |  Page : 179-180

Sebacbous naevus with chronic leg ulcers




Correspondence Address:
R R Mittal


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How to cite this article:
Mittal R R, Walia R, Chopra A K. Sebacbous naevus with chronic leg ulcers. Indian J Dermatol Venereol Leprol 1994;60:179-80

How to cite this URL:
Mittal R R, Walia R, Chopra A K. Sebacbous naevus with chronic leg ulcers. Indian J Dermatol Venereol Leprol [serial online] 1994 [cited 2019 Oct 20];60:179-80. Available from: http://www.ijdvl.com/text.asp?1994/60/3/179/4037


To the Editor,

Sebaceous naevi (SN) can be found in about 0.3% of all neonates. [1] SN is usually located on the scalp or face at birth as linear, oval or round hairless plaque. Usually SN are single but may be multiple or extensive. Extensive SN show associated CNS, eye or skeletal deformities. [2] Mental retardation and epilepsy may be associated . [3] SN and verrucous epidermal naevi are very closely related and may represent variants. [4] Histopathologically, SN in children show cords of undifferentiated hair cells simulating embryonic hair follicles, some hairs have dilated keratin filled infundibula with multiple . buds of undifferentiated cells. At puberty, SN show large number of mature or nearly mature sebaceous glands with papillomatous hyperplasia of overlying epidermis with changes as seen in children. [5] Malignant change can superimpose secondarily in middle age or even earlier.

A 22-year-male was admitted with chronic venous leg ulcers since 2 years. In addition he had 2 plaques on the chin and right cheek since early childhood with rapid progression at puberty. He had epilepsy at the age of 5 which was treated. He had low intelligence and bilateral iridocyclitis. Bigger plaque on chin was 11 X 7.5 cm, firm, non­tender, mobile in certain drections, pinkish­brownish with well defined margins right side and ill defined on left and lower side. Its surface was smooth, velvetty, thrown into folds, sparse hairs were present in the centre of plaque with alopecia on either side. Similar 1.5 x 1.0 cm plaque was seen on the outer side of right angle of mouth. Systemic examination and routine investigations were normal. Histopathology revealed multiple mature sebaceous glands with peripheral mononuclear infiltration, giant cells and papillomatous hyperplasia of overlying epidermis.

SN are reported to be common type of naevi but we see them rarely in our area. The present case was a type of SN and association of chronic leg ulcers may be coincidental.

 
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1.Alper J, Holmes L B, Mihm M C. Birthmarks with serious medical significance: nervocellular naevi, sebaceous naevi and multiple cafe-au-lait spots. J Paediatr 1979; 95 : 696-700.  Back to cited text no. 1    
2.Hornstein OP, Knickenberg M. Zur Kenntnis des schimmel-penning-Fenerstein-Mims­Syndromes. Arch Dermatol Fsch 1974; 250: 33-50.  Back to cited text no. 2  [PUBMED]  
3.Fenerstein R, Mims L. Linear nevus sebaceous with convulsions and mental retardation. Amer J Dis Child 1962; 104: 675-9.  Back to cited text no. 3    
4.Antberton D J. Naevi and other developmental defects. In: Textbook of Dermatology (Rook A, Wilkinson DS, Ebling FJG, eds), 5th edn. Oxford: Blackwell Scientific publications, 1992; 456-7.  Back to cited text no. 4    
5.Lever WF, Schaumburg-Lever G. Tumors of epidermal appendages. In : Histopathology of the Skin, 7th Edn. Philadelphia : J B Lippincott, 1990; 594.  Back to cited text no. 5    




 

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