|Year : 1992 | Volume
| Issue : 4 | Page : 283-284
Striae atrophicans due to topical fluocinolone acetonide
Source of Support: None, Conflict of Interest: None
A 27-year old woman developed striae atrophicans on her left posterior axillary fold 25 days after daily local massage of fluocinolons acetonide 0.1%.
Keywords: Striae atrophicans, fluocinolone acetonide
|How to cite this article:|
Gupta R. Striae atrophicans due to topical fluocinolone acetonide. Indian J Dermatol Venereol Leprol 1992;58:283-4
| Introduction|| |
Use of topical steroids can cause several side effects, one of them is the development of striae. It has been suggested that these side effects are very infrequently seen in Indian patients.  A case of vitiligo in which striae developed 25 days after daily use of 0.1% fluocinolone acetonide ointment is reported.
| Case Report|| |
A-27-years-old woman presented with lesions of vitiligo around her neck, left posterior axillary fold, sternum, under both breasts, left cubital fossa, and left leg for past 2 months. The author started levamisole 150 mg on 2 consecutive days every week along with local massage of 0.1% fluocinolone acetonide ointment, however she developed streaks of atrophy on her left posterior axillary fold [Figure - 1]. There was no atrophy of the skin on other areas. There was no other sign of Cushing's syndrome. Application of topical fluocinolone acetonide ointment was stopped on her left axilla, however it was continued on other sites, During the next 1 month all vitiliginous macules cleared and the topical fluocinolone acetonide and systemic levamisole were stopped by the patient. During the next 2 months she developed recurrence of the vitiligo macules on her left axilla and neck. There was no change in the striae atrophicans on her left posterior axillary fold.
| Comments|| |
Striae are commonly seen in Cushing's syndrome. Absence of striae on other parts of the body and other features of Cushing's . syndrome rule out the possibility of it been responsible for producing striae in this case. Unilateral appearance of the striae only on the left posterior axillary fold suggests it relationship to the fluocinolone actinide application. However its absence from the places of application suggest that intertriginous axillary fold along with vigorous massage provided occlusion, analogous to the occlusive dressing. Chernosky and Knox  reported 2 cases who developed atrophic striae on abdomen_ and leg after 3 and 9 months respectively due to occlusive corticosteroid application.
Pavithran  reported development of striae after 4, 18, and 22 months of use of topical steroid in 3 patients. This case is reported due to the appearance of striae in a very short time i.e., 25 days.
| References|| |
|1.||Pavithran K. Topical corticosteroid induced atrophic striae and tinea incognito. Ind J Dermatol Venereol Leprol 1986; 52: 351-4. |
|2.||Chernosky M E, Knox J M. Atrophic str4ae after occlusive corticosteroied therapy. Arch Dermatol 1964; 90: 15-9. |
[Figure - 1]