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LETTER TO EDITOR
Year : 1992  |  Volume : 58  |  Issue : 1  |  Page : 55

Neurofibromatosis in association with vitiligo




Correspondence Address:
K K Singh


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Source of Support: None, Conflict of Interest: None


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How to cite this article:
Singh K K, Kumar A, Mohan L, Mukhija R D, S. Neurofibromatosis in association with vitiligo. Indian J Dermatol Venereol Leprol 1992;58:55

How to cite this URL:
Singh K K, Kumar A, Mohan L, Mukhija R D, S. Neurofibromatosis in association with vitiligo. Indian J Dermatol Venereol Leprol [serial online] 1992 [cited 2019 Aug 17];58:55. Available from: http://www.ijdvl.com/text.asp?1992/58/1/55/3751


To the Editor,

A 45-year-old male patient presented with several nodules of 20 years duration and hypopigrnented macules of 7 years duration. Seven cafe-au-lait spots of more than 1.5 cm in diameter and axillary freckling were also seen.

Patient's father had similar nodules. Histologically the nodules in patient were neurofibromas and the hypopigmented lesions were vitiligo.

Chemical mediators produced from the nerve endings may be responsible for destruction of melanocytes or inhibition of melanin synthesis. [1] To the best of our knowledge no such case of neurofibromatosis associated with vitiligo has been reported in the literature.

 
  References Top

1.Mosher DB, Fitzpatrick TB, Ortonne JP, et al. Disorders of Pigmentation. In : Dermatology in General Medicine (Fitzpatrick TB, Eisen AZ, Wolf K, et al eds), 3rd edn. NewYork McGraw-Hill Book Company, 1987; 817.  Back to cited text no. 1    




 

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Online since 15th March '04
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