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Year : 1991  |  Volume : 57  |  Issue : 6  |  Page : 319

Pagetoid bowen's disease of the unexposed skin

Correspondence Address:
K B Logani

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Source of Support: None, Conflict of Interest: None

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How to cite this article:
Logani K B, Bedi B, Pai S, Chandra A, Lal S. Pagetoid bowen's disease of the unexposed skin. Indian J Dermatol Venereol Leprol 1991;57:319

How to cite this URL:
Logani K B, Bedi B, Pai S, Chandra A, Lal S. Pagetoid bowen's disease of the unexposed skin. Indian J Dermatol Venereol Leprol [serial online] 1991 [cited 2020 Sep 19];57:319. Available from:

To the Editor,

A 65-year-old female presented with gradually increasing collection of multiple blackish papules with rough surface and well defined margins in the left popliteal fossa. A skin biopsy was performed.

Microscopically, epidermis showed mod­erate hyperkeratosis, hypergranulosis, acanthosis with blunted and thickened rete pegs. There was complete disarray of spinous cells in the full thickness of stratum spinosum with marked nuclear pleomorphism and ana­plasia. Focal dyskeratotic cells showing indi­vidual cell keratinization with atypical hyperchromatotic nucleus surrounded by punched out clear cytoplasm were dispersed throughout full thickness of the epidermis. There was no invasion of the basement membrane. The dermis was unremarkable.

Pagetoid cells in Bowen's disease show dyskeratosis and contain glycogen a feature not observed in Paget's disease. No evidence of either arsenic therapy or presence of any overt visceral malignancy was elicited in the present case.[2]

  References Top

1.Lever WF : Histopathology of the skin, Ed 6th 1983; p 496-98.  Back to cited text no. 1    
2.Raiter K, Perierac, Ackerman AB . Pagetoid Bowens disease versus extra mammary Pagets disease, J Dermatol Surg Oncol, 1976; 2 : 24-25.  Back to cited text no. 2    


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