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Year : 1991  |  Volume : 57  |  Issue : 6  |  Page : 315

Linear epidermal naevus with acantholytic dyskeratosis

Correspondence Address:
P K Guha

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How to cite this article:
Guha P K. Linear epidermal naevus with acantholytic dyskeratosis. Indian J Dermatol Venereol Leprol 1991;57:315

How to cite this URL:
Guha P K. Linear epidermal naevus with acantholytic dyskeratosis. Indian J Dermatol Venereol Leprol [serial online] 1991 [cited 2020 Sep 19];57:315. Available from:

To The Editor,

A 5 year old boy presented with multiple erythematous papular keratotic verrucosus le­sions since birth, beginning on the lateral as­pect of the left thigh extending upto the left second toe but not involving the sole. The width varied averaging less than 5 cm. The lesion assumed a zosteriform configuration at the thigh upto popliteal fossa wherefrom it became linear upto the second toe. Also small erythematous micropapular lesions 5 cm in length appeared at birth in the midline of the body at the suprapubic region extending upto the root of the penis in a strictly linear fashion. A same type of lesion 5 cm in length was also present in the chin since birth. These two lesions were nonprogressive and symptomless. The thigh lesions were itchy with excoriation and healed by scarring. There was no family history. Biopsy showed hyperkeratosis, acanthosis and extensive acantholysis which was most prominent in the suprabasal region but extended throughout the whole thickness of epidermis. Corps-ronds were scanty.

Multiple unilateral keratotic lesions, found in a linear or zosteriform pattern have been reported in the past as unilateral keratosis follicularis [1] or as a linear epidermal nevus with the histologic features of keratosis follicularis [2]. In Darier's disease the skin lesions appears between 8 to 16 years of age. In our case the lesions appeared since birth and there was no seasonal variation ever, which goes against Darier's disease. The gross histologi­cal features of acantholytic dyskeratosis, presence of lesions since birth which is un­usual for Darier's, and absence of seasonal variation leads us to designate the case as linear epidermal naevus with acantholytic dyskeratosis which has also been proposed by Lever [3].

  References Top

1.Ackerman AB; Goldman G : Combined epidermolytic hyperkeratosis and focal acantholytic dyskeratosis. Arch Dermatol; 1974;385-386.  Back to cited text no. 1    
2.Leeming JAL : Acquired linear nevus showing his­tological features of keratosis foticularies. Brit J Dermatol; 1969; 81 : 128-131.  Back to cited text no. 2    
3.Lever Walter F; Lever Gundula Schaumburg Histopathology of the Skin; 7th ed. J.B.Lippincott Company, Philadelphia; 1990; P 525.  Back to cited text no. 3    


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