IADVL
Indexed with PubMed and Science Citation Index (E) 
 
Users online: 3995 
     Home | Feedback | Login 
About Current Issue Archive Ahead of print Search Instructions Online Submission Subscribe What's New Contact  
  Navigate here 
  Search
 
   Next article
   Previous article 
   Table of Contents
  
 Resource links
   Similar in PUBMED
    Search Pubmed for
    Search in Google Scholar for
  Related articles
   [PDF Not available] *
   Citation Manager
   Access Statistics
   Reader Comments
   Email Alert *
   Add to My List *
* Registration required (free)  

 
  In this article
   Abstract
   Case report
   Comments
   References
   Article Figures

 Article Access Statistics
    Viewed3632    
    Printed39    
    Emailed0    
    PDF Downloaded0    
    Comments [Add]    
    Cited by others 1    

Recommend this journal

 


 
CASE REPORT
Year : 1991  |  Volume : 57  |  Issue : 3  |  Page : 146-147

Relapsing polychondritis




Correspondence Address:
P T Thankappan


Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

  Abstract 

A 35-years-old man presented with the classical features of relapsing polychondritis, namely bilateral auricular chondritis, iridocyclitis, episcleritis, rhintis and polyarthralgia with typical histological features. Patient was treated with dapsone without any benefit and short course of steroids caused regression of the condition.


Keywords: Relapsing polychondritis.


How to cite this article:
Thankappan P T, Sulochana G. Relapsing polychondritis. Indian J Dermatol Venereol Leprol 1991;57:146-7

How to cite this URL:
Thankappan P T, Sulochana G. Relapsing polychondritis. Indian J Dermatol Venereol Leprol [serial online] 1991 [cited 2019 May 23];57:146-7. Available from: http://www.ijdvl.com/text.asp?1991/57/3/146/3653


Relapsing polychondritis (RP) is a fairly rare disorder where the manifestations are often widespread and are clinically and pathologically impressive or even dramatic[1]. It usually affects middle aged men and are manifested by bilateral auricular chondritis, non-invasive seronegative polyarthritis, nasal, chondritis, ocular inflammation, respiratory chondritis and audio-vestibular damage[2]. We are presenting a case of relapsing poly chondritis being a rare dermatologic problem.


  Case report Top


A 35-year-old male clerk presented with multiple erythematous, slowly progressive tender nodules and plaques over the both pinnas of his ears of 3 months duration. Lob­ules of the ear were completely spared. Since last 6 months he had recurrent attacks of rhinitis and arthritis of larger joints. He had an iridocyclitis of the left eye one year back which was treated with steroids, by an Oph­thalmologist. Episcleritis of the left eye was present. No systemic abnormality was de­tected during physical examination.

Laboratory investigations revealed a per­sistently raised ESR, and VDRL, Rose water test, L. E. Cells test were negative. Skin clip­ping and scrapings for AFB was negative. Skin biopsy showed an apparently normal epidermis and upper dermis. The cartilage cells appeared degenerated with vacuolization,

nuclear pyknosis and loss of basophilia. A dense inflammatory infiltrate consisting of neutrophils, lymphocytes, plasma cells and macrophages were seen among the degener­ated cartilage cells.

Classical clinical features namely auricu­lar chondritis, rhinitis, ocular inflammation with typical histopathology, a diagnosis of relaps­ing polychondritis was made and the patient was treated with prednisolone 30 mg daily and was tapered and stopped within a period of 4 months. The lesions improved dramati­cally with steroids.


  Comments Top


Relapsing polychondritis is a rare disorder and it's presentation to a dermatologist is still rare. To the best of our knowledge this case is the first to be reported in the dermatologic literature in India. Though dapsone was re­ported to be effective in relapsing polychondritis[3].[4] our case did not respond to dapsone. Katz also experienced similar results with dapsone.[5]

 
  References Top

1.Pearson CM : Relapsing polychondritis, in Arthritis and allied conditions, 9 th edition, Editors McCarthy DJ, Lea & Febiger, Philadelphia, 1979; 188-90.  Back to cited text no. 1    
2.West PDB : Relapsing polychondritis, an unusual presentation, J Laryngol Ottol, 1988; 102 : 254­255.  Back to cited text no. 2    
3.Barranco P et al : Treatment of Relapsing polychondritis with depsone, Arch Dermatol,1976; 112 : 1286.  Back to cited text no. 3    
4.Martin J et al Relapsing polychondritis treated with dapsone, Arch Dermatol,1976; 112 : 1272, 74.  Back to cited text no. 4    
5.Katy SI : Relapsing Polychondritis, in Dermatology in General Medicine, third edition, edited by Fitzpatrick TB, Eisen AZ, Wolff K et al, McGraw­Hill Book Company. New York, 1987; 1852-54.  Back to cited text no. 5    


    Figures

[Figure - 1]

This article has been cited by
1 Relapsing polychondritis - Delayed diagnosis and fatal outcome
Patel, K.
Indian Journal of Dermatology, Venereology and Leprology. 2010; 76(1): 67-69
[Pubmed]



 

Top
Print this article  Email this article
Previous article Next article

    

Online since 15th March '04
Published by Wolters Kluwer - Medknow