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 ORIGINAL CONTRIBUTIONS
Year : 1990  |  Volume : 56  |  Issue : 6  |  Page : 427--429

Serum testosterone, DHEA-S and androstenedione levels in acne



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A Hatwal


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Basal serum levels of total testosterone, dehydroepiandosterone sulfate (DHEA, - S) and androstenedione (A4) were measured by radioimmunoassay in 100 patients of acne vulgaris, and in 100 age and sex matched acne free healthy subjects. In males with acne the mean serum testosterone levels were marginally and the DHEAS and A4A levels were significantly higher as compared to controls (p). Females with acne had significantly higher levels of testosterone (p<0.001), DHEA-S (p<0.001) and (p < 0.01) than controls. Our data suggest that increased adrenal androgen levels in plasma may be responsible for treatment resistant acne vulgarism






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Online since 15th March '04
Published by Wolters Kluwer - Medknow