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Year : 1990  |  Volume : 56  |  Issue : 5  |  Page : 377--380

Topical clindamycin hydrochloride 1% in acne vulgaris

Correspondence Address:
Vaswani N Khanna

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Source of Support: None, Conflict of Interest: None

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Twenty six patients with moderately severe acne were treated for 12 weeks with topical clindamycin hydrochloride 1% (12 patients) and the vehicle (14 patients). A good or excellent reduction was seen in the non-inflammatory acne lesion count in 3 (25%) of the patients on topical clindamycin and in none of the patients who used the vehicle (control).While 9 (75%) of the patients using topical clindamycin hydrochloride showed a good to excellent response in their inflammatory acne lesion count, only 2 (14.29%) of the control group showed a similar response. The response of the non-inflammatory acne to topical clindamycin hydrochloride 1% was comparable to that of the vehicle, (p >0.05) while the response of inflammatory acne lesions to topical clindamycin hydrochloride 1% was superior to that of the vehicle (p <0.05)

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Online since 15th March '04
Published by Wolters Kluwer - Medknow