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Year : 1990  |  Volume : 56  |  Issue : 5  |  Page : 367--370

Measurement of some biophysical parameters in skin lesions of leprosy

Correspondence Address:
A B Gupta

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Source of Support: None, Conflict of Interest: None

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Transepidermal water loss (TEWL), high frequency electrical conductance (HFC) and the hydration state index (HSI) were measured in sldn lesions of 30 paucibacillary leprosy patients and compared with the contralateral uninvolved skin. While the TEWL, HFC and HSI all showed lower values in the lesion site, as compared to the contralateral skin sites, the differences between the two sets of values significant in HFC and. HSI only at 2% and 1% level respectively. A significant positive correlation (r = 0.69) was found to eidst between these two parameters. The parameters correlate well with the known reduced sweating in skin lesions of TT and BT leprosy and may therefore be considered as good objective parameters to confirm hypohydrosis in suspected skin lesions ofleprosy.

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Online since 15th March '04
Published by Wolters Kluwer - Medknow