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 ORIGINAL CONTRIBUTIONS
Year : 1990  |  Volume : 56  |  Issue : 3  |  Page : 208--210

Cerebro-spinal fluid examination in early syphilis after treatment with penicillin



Correspondence Address:
S Talwar


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In case s having early syphilis, cerebro-spinal fluid:(CSF) was examined 6 months following pencillin treatment in 1173 cases of which 1 case showed some abnormality. In 1288 cases, CSF examination done at 30 months or later revealed abnormality in 3 cases. The initial diagnosis in these cases was primary syphilis in 2 cases and secondary syphilis in the remaining 2 and these cases had initially been treated with 2.4 MU of benzathine penicillin. These 4 cases were now diagnosed as cases of asymptomatic nourosyphifis and retreated with 9 MU Of procaine penicillin. AU these cases were cured following retreatment. Considering this small number (0.17%), it is considered unessential to examine CSF as a routine in early -syphilis.' However in cases where the clinical or serological response to treatment is not satisfactory, CSF examination is advisable.






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Online since 15th March '04
Published by Wolters Kluwer - Medknow