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Year : 1988  |  Volume : 54  |  Issue : 5  |  Page : 258--259

Summer Variant of Autosmal Dominant Ichthyosis Vulgaris

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PMID: 28134199

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Eleven cases of mild autosomal dominant ichthyosis vulgaris (ADIV) were seen who presented with asymptomatic, brownish-black hyper keratotic lesions' over the flexure surfaces of wrists, dorsum of hands, knees and ankles for 1-2 months during peak summer months. The lesions disappeared with the onset of monsoon. All these cases had typical lesions of ADIV during winter months. This paradoxical phenomenon of ichthyosis alternating with hyperkeratotic pigmented lesions in the same individual during different seasons remains unexplained. Treatment with 20% urea cream and oral vitamin A had no effect on the course of the disease.


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Online since 15th March '04
Published by Wolters Kluwer - Medknow