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Year : 1988  |  Volume : 54  |  Issue : 5  |  Page : 247--250

Okt6 Positme Epidermal L4ngerhans Cells in Tinea Corporis

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PMID: 28134196

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Langerhans cells (LC) were defined by indirect immunofluoresence using OKT6 monoclonal antibody in the skin lesions of 11 untreated patients with tinea corporis. The number and distribution of OKr6 + epidermal LC in the lesions was very low in comparison to that found in the normal skin. In most of the lesions, T6 + LC could not be seen in the epidermis. A like antigens were not detectable on the keratinocytes. These observations suggest deceased CMI response to the fungal infection and that the reduction in LC may be a contributing factor in the pathogenesis of tinea corporis.


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Online since 15th March '04
Published by Wolters Kluwer - Medknow