| ORIGINAL CONTRIBUTION
|Year : 1988 | Volume
| Issue : 5 | Page : 247--250
Okt6 Positme Epidermal L4ngerhans Cells in Tinea Corporis
RB Narayanan, A Girdhar, RK Lavania, BK Girdhar
Langerhans cells (LC) were defined by indirect immunofluoresence using OKT6 monoclonal antibody in the skin lesions of 11 untreated patients with tinea corporis. The number and distribution of OKr6 + epidermal LC in the lesions was very low in comparison to that found in the normal skin. In most of the lesions, T6 + LC could not be seen in the epidermis. A like antigens were not detectable on the keratinocytes. These observations suggest deceased CMI response to the fungal infection and that the reduction in LC may be a contributing factor in the pathogenesis of tinea corporis.
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