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Year : 1988  |  Volume : 54  |  Issue : 1  |  Page : 21--23

Histochemical Profile of Vitiligo

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PMID: 28134171

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Fifty untreated vitiligo patients were subjected to histo-chemical examination using dopa reaction technique. Dopa positive melanocytes were absent in a large majority (82%) of cases. Increase in the number of supra-basal clear cells was observed in 70 percent. Presence of inflammatory infiltrate at dermo- epidermal junction along with basal cell layer-dissolution was seen in 7 cases. Grayish-black, void cells considered to be inactive melanocytes, were seen in the basal layer.


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Online since 15th March '04
Published by Wolters Kluwer - Medknow