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Year : 1987  |  Volume : 53  |  Issue : 6  |  Page : 329--331

Sebo-suppression by Combined Anti-androgen and Oestrogen in Female Acne Compared with Tetracycline

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PMID: 28145345

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Cyclic administration of a combination of cyproterone acetate and ethinyl oestradiol in 30 female acne patients led to a significant decrease of the cutaneous sebum excretion rate (SER) as assessed by the modified gravimetric technique. The mean percent reduction was 36.42 + 3. 07 at the end of 6 months, and, it remained reduced even after a treatment free period of 3 month. In comparison, tetracycline treated patients showed a slight rise in the SER that returned to near baseline values 3 months after cessation of the drug.


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Online since 15th March '04
Published by Wolters Kluwer - Medknow