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Year : 1983  |  Volume : 49  |  Issue : 2  |  Page : 61--64

Effect of Prothionamide in Leprosy Clinico-bacteriological Observations

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Source of Support: None, Conflict of Interest: None

PMID: 28176708

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Mouse footpad studies indicate the strong, I bactericidal property of prothionamide against M. leprae supported with limited clinical experience. Based on the recommendation made by the Expert Committee on Experimental Chemotherapy, Mexico as well as by Ellard, 6 L L and 2 BL cases were administered prothionamide alone 500 mg and 250-375 mg daily for a period of 3 -6 months. Maximum fall of MI up to 99% was observed by the end of second month correlated with marked clinical improvement.


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Online since 15th March '04
Published by Wolters Kluwer - Medknow