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| Year : 1963 | Volume
: 29
| Issue : 4 | Page : 131--140 |
Diagnosis and Management of Reactions in Leprosy
KK Koticha
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Correspondence Address:
K K Koticha
The three main groups of leprosy are tuberculoid, intermediate and lepromatous. Factors known to precipitate reactions in leprosy are diseases - like typhoid, malaria, dysentery, ankylostomiasis and influenza, diet, climatic changes, mental stress, small pox vaccination, late months of pregnancy, childbirth, drugs like sulphonamides, sulphur derivatives and iodides. The three types of reactions are 1) ALR 2) PLR 3)ENL. The treatment of reaction is firstly to stop DDS and substitute by diphenylthiourea (DPT). In case DPT is not available, DDS can be substituted by less toxic sulphones like promin or sulphetrone. Antibiotics and other drugs found useful are colchicoside, butazolidine and irgapyrine. Beneficial drugs whose use is empirical are methylene blue (MB), antimony compounds and adrenaline chloride if symptomatic treatment, MB etc fail to control reactions the only alternative is to use corticosteroids sparingly.
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